• Login
No Result
View All Result
Gujarat Journal
  • Home
  • Gujarat News
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
    • Photography
  • Tech
    • App News
  • Auto
  • Others
    • Sports
    • Agriculture
    • Science
    • Astrology
    • Finance/Money
    • Press Release
    • Religion
  • Home
  • Gujarat News
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
    • Photography
  • Tech
    • App News
  • Auto
  • Others
    • Sports
    • Agriculture
    • Science
    • Astrology
    • Finance/Money
    • Press Release
    • Religion
No Result
View All Result
Gujarat Journal
No Result
View All Result
Home Lifestyle Health & Fitness

Cord Blood transplant outperforms bone marrow transplant states a new study by ASH

by Gujarat Journal Team
March 31, 2021
in Health & Fitness
Reading Time: 3 mins read
A A
0
Share on FacebookShare on Twitter
  • Published in the journal – Blood Advances – the studies aim to study the efficacy of cord blood in treatment of diverse disorders

  • Studies’ outcome crucial for multi-ethnic country like India, where the chances of finding a matching donor are very low.

New Delhi: American Society of Hematology (ASH), the world’s largest professional society working to conquer blood diseases has recently released two key studies on cord blood transplants, as part of its Blood Advances journal. Led by a team of leading researchers from University of Colorado and University of Pittsburgh, the two studies have brought to foray the various benefits of cord blood transplant over bone marrow in cancerous and non-cancerous disorders. With the growing concerns among medical fraternity about finding matching bone marrow donors in a multi-ethnic country like India, the findings of the studies clearly outline the efficacy of cord blood in the treatment of diverse disorders.

In the study conducted to weigh benefits of cord blood transplant over bone marrow transplant for cancerous disorders, University of Colorado researchers compared the outcomes of matched bone marrow and double-unit cord blood transplants in adults. Amongst the 313 patients studied (190 cord blood transplant and 123 matched related donor transplant patients), the two key findings emerged. One, Chances of developing graft versus host disease were higher with bone marrow as compared to cord blood transplants and two, it was discovered that relapse rates were lower in patients who received a cord blood transplant.

You May AlsoLike This

Healing Little Hearts: Dr. Prashant Bobhate Leads Early CHD Detection

Healing Little Hearts: Dr. Prashant Bobhate Leads Early CHD Detection

May 17, 2025
Patna Welcomes World-Class Mental Health Care Through Dr. Vivek Pratap Singh’s Unique Neuro & Child Psychiatry Services

Patna Welcomes World-Class Mental Health Care Through Dr. Vivek Pratap Singh’s Unique Neuro & Child Psychiatry Services

May 12, 2025

Rooted in Breath: Sagar Uddhav Shende’s Path to Pancha Koshas

April 29, 2025

MYOGENETIX: Introducing High-Performance Sports Nutrition In India

March 19, 2025

Followed by the findings of the first study, a second study on the efficacy of cord blood transplant among non-cancerous disorders was also undertaken by a team of researchers from University of Pittsburgh. The researchers successfully treated 44 children suffering from various non-cancerous & immune disorders with a combination of low dose chemotherapy and single-unit of HLA-mismatched cord blood with no cell expansion. The successful outcomes provided by this first of its kind and the largest trial showed that cord blood outperformed bone marrow in terms of graft failure, treatment related mortality and event-free survival. Also, this gives tremendous confidence to patients & doctors in a multi-ethnic country like India where the chances of finding a matching donor are very low.

Commenting on this, Dr. Sunil Bhat, MBBS, MD (Pediatrics) Mazumdar Shaw Cancer Centre, Narayana Health City, Bengaluru said, “Authors have tried a new conditioning regimen which is “reduced toxicity” hence less toxic to the patients but at the same time quite effective resulting into good outcomes in these difficult disease conditions. The application of “immune boost” post-transplant is also novel and results into better immune recovery and less complications especially of infections post cord blood transplant.”

“Another study which was published during same year gives a clear understanding on how to select a cord blood donor based on Human Leukocyte Antigens (HLA) match and also makes clear recommendations on the stem cell dose required for successful transplant. This study is also a great guide to the physicians to select cord blood donors for transplant purpose.

Other key highlights from the studies:

Study 1 – To understand the efficacy of Cord Blood transplants over bone marrow for Cancerous disorders

  • Outcomes of this study demonstrated that cancer patients undergoing cord blood transplants showed better improvement & developed lesser complications than those who received matched sibling donor transplants.
  • The overall improved recovery rate and lack of complications resulted in low costs associated with post-transplant care.
  • This treatment protocol had a distinct positive impact on the patients’ quality of life.

 

Study 2 – To understand the efficacy of Cord Blood transplants over bone marrow for non-cancerous disorders

  • The graft failure rate of <5% seen in this trial is the lowest ever reported for non-manipulated cord blood grafts in non-cancerous or even in cancerous diseases.
  • The lowest 1-year (Treatment-Related Mortality) TRM of 5%, resulting in >90% Event Free Survival (EFS) at 1 year was reported.
  • A single unit of allogeneic cord blood could be identified for each of the 44 eligible children regardless of their ethnicities, showing the unique and unparalleled suitability of cord blood grafts even without being perfectly (HLA) matched.
  • No cell expansion was required in the trial. In general, a single cord blood unit doesn’t have sufficient stem cells to treat adults.
  • No patient developed severe chronic graft versus host disease and a distinct improvement in the quality of life was reported.
  • The novel treatment protocol used in the trial prevented graft failure and aided immune reconstitution.
ShareTweetShareSendShareShareSendPin
Previous Post

A women-led startup develops deep-tech for reliable low-cost internet services to rural areas

Next Post

New hope for mitochondrial disorders

Related Posts

Healing Little Hearts: Dr. Prashant Bobhate Leads Early CHD Detection
Health & Fitness

Healing Little Hearts: Dr. Prashant Bobhate Leads Early CHD Detection

May 17, 2025
Patna Welcomes World-Class Mental Health Care Through Dr. Vivek Pratap Singh’s Unique Neuro & Child Psychiatry Services
Health & Fitness

Patna Welcomes World-Class Mental Health Care Through Dr. Vivek Pratap Singh’s Unique Neuro & Child Psychiatry Services

May 12, 2025
Rooted in Breath: Sagar Uddhav Shende’s Path to Pancha Koshas
Health & Fitness

Rooted in Breath: Sagar Uddhav Shende’s Path to Pancha Koshas

April 29, 2025
MYOGENETIX: Introducing High-Performance Sports Nutrition In India
Health & Fitness

MYOGENETIX: Introducing High-Performance Sports Nutrition In India

March 19, 2025
Aveya IVF & Fertility Center Launches Affordable Egg Freezing and IVF Packages in Delhi
Health & Fitness

Aveya IVF & Fertility Center Launches Affordable Egg Freezing and IVF Packages in Delhi

March 13, 2025
Reborn Skin & Hair Clinic: Transforming Aesthetics in Pune and Jaipur
Health & Fitness

Reborn Skin & Hair Clinic: Transforming Aesthetics in Pune and Jaipur

January 16, 2025

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Recommended

Healing Little Hearts: Dr. Prashant Bobhate Leads Early CHD Detection

Healing Little Hearts: Dr. Prashant Bobhate Leads Early CHD Detection

16 hours ago
From Cardboard to Creativity: Best Jugaad Entries So Far

From Cardboard to Creativity: Best Jugaad Entries So Far

2 days ago

Trending

Patna Welcomes World-Class Mental Health Care Through Dr. Vivek Pratap Singh’s Unique Neuro & Child Psychiatry Services

Patna Welcomes World-Class Mental Health Care Through Dr. Vivek Pratap Singh’s Unique Neuro & Child Psychiatry Services

5 days ago
Haldiram’s Restaurant continues its expansion in the heart of Surat

Haldiram’s Restaurant continues its expansion in the heart of Surat

2 years ago

Popular

Girgiti – God with Many Faces: A Shape-Shifting Tale of Morality and Justice

Girgiti – God with Many Faces: A Shape-Shifting Tale of Morality and Justice

9 months ago

CosmicNeurons a startup by Prof. Prashant Singhal will help you shape your career in the right direction !!

3 years ago
Urology in Surat, Drug-Coated Balloon Urethroplasty, Dr Subodh Kamble, internationally renowned Urologist, Prish Multi Speciality Hospital & Center for Urocare, Surat

Breakthrough in Urology in Surat: Successful Drug-Coated Balloon Urethroplasty Performed on 84-Year-Old Male Patient

1 year ago
Bela: Gujarati Urban Film Is a Movement in Itself, Not Just a Movie

Bela: Gujarati Urban Film Is a Movement in Itself, Not Just a Movie

1 week ago
Tapi Utsav 2024: A Celebration of Art, Culture, and Dialogue in Surat

Tapi Utsav 2024: A Celebration of Art, Culture, and Dialogue in Surat

1 year ago

Gujarat Journal, digital news and story platform bring you the news, articles, stories, and opinions on the latest happenings worldwide covering various sectors like nation, politics, and governance, social sector, review, foreign affairs, defence and security, latest review, lifestyle, entertainment, sports, technology, auto sectors, education, business and start-ups updates, Agriculture, Science, finance, money, food, and culture, etc.

Category

  • Agriculture
  • App News
  • Astrology
  • Auto
  • Business
  • Education
  • Entertainment
  • Fashion & Beauty
  • Finance/Money
  • Food
  • Gujarat News
  • Health & Fitness
  • India
  • Lifestyle
  • National
  • Photography
  • Politics
  • Press Release
  • Religion
  • Science
  • Social Work
  • Sports
  • State News
  • Tech
  • Travel
  • Uncategorized
  • World

Follow Us

  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News

Copyright © 2022 Gujarat Journal

No Result
View All Result
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Home
  • Privacy Policy

Copyright © 2022 Gujarat Journal

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In